has part has core process negative regulation of AKT signaling [Ground glass appearance] phenobarbital accumulation in liver [Ground glass appearance] reactive oxygen species biosynthetic process [Ground glass appearance] positive regulation of mitochondrial membrane permeability [Ground glass appearance] decreasing mitochondrial membrane potential [Ground glass appearance] apoptotic process [Ground glass appearance] ground glass appearance with Cytochrome P450 activation by phenobarbital The totality of all processes through which ground glass appearance is realized. This toxic course has a process of Cytochrome P450 (CYP) activation by phenobarbital. hyperfunction of glucuronic acid conjugation for phenobarbital intermediate metabolite [Ground glass appearance] hyperfunction of increasing the amount of phenobarbital [Ground glass appearance] hyperfunction of moving phenobarbital to the inside of liver [Ground glass appearance] ground glass appearance with Cytochrome P450 activation [toxic course] phenobarbital metabolism imbalance [Ground glass appearance] hyperfunction of phenobarbital metabolism phase I by Cytochrome P450 [Ground glass appearance] smooth endoplasmic reticulum proliferation in hepatocyte [Ground glass appearance - Cyp - PB]