has part has attribute value has attribute high level imbalance state state of functional supply very high level functional demand state toxicological imbalance VH (toxic action) toxicological imbalance H<VH In the imbalance model, the basic units are as follows: 1) a functioning process (supply) for biological defense and maintaining homeostasis; 2) a functional demand process (demand) as toxic activity; 3) balance/imbalance between toxic activity and defense processes; and 4) outcome from organelles, cells, or tissues to the organ exhibiting toxicity manifestations. This entity is a compound state that inculdes step 1 to 4. The defense performance level is higher (H) than daily life; however, the functional demand level is Very high(VH), which leads to the imbalance and leads to toxicity manifestation. power (attribute)