<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/TXPO?iri=http://purl.obolibrary.org/obo/TXPO_0001964"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- xsd:string -->

    <rdfs:Datatype rdf:about="xsd:string"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0000004 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/TXPO_0000004">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has core process</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/TXPO_0001964 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0001964">
        <rdfs:label rdf:datatype="xsd:string">phospholipidosis (latent)</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/TXPO_0003382"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0002293"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0003678"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/TXPO_0000004"/>
                <allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0002293"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0004933"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0002522"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0005189"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0002273"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0005059"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:15342952</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:16979167</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:22960355</oboInOwl:hasDbXref>
        <ns4:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The totality of all processes through which the phospholipidosis is realized. This entity represents latent phospholipidosis, which describes the course of processes before toxic manifestation.
 In the drug exposure situation in phospholipidosis, it is known that CADs affect biological functioning. CADs bind to lysosomal membranes and form a complex with phospholipids, which negatively regulates phospholipid degradation. Therefore, the defence system cannot perform a ‘high’ level, i.e. there is a lack of adaptation. Under normal conditions, although the cell system can maintain the balance between increasing and decreasing phospholipid at a ‘medium’ level, in this state, the cellular system is in what is called the latent stage.</ns4:IAO_0000115>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0002273 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0002273">
        <rdfs:label rdf:datatype="xsd:string">maintaining phospholipid homeostasis [Phospholipidosis (latent)]</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0002293 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0002293">
        <rdfs:label rdf:datatype="xsd:string">phospholipid metabolism balance [Phospholipidosis (latent) ]</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0002522 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0002522">
        <rdfs:label rdf:datatype="xsd:string">CAD accumulation in lysosome [Phospholipidosis (latent)]</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0003382 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0003382">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">phospholipidosis (course)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0003678 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0003678">
        <rdfs:label rdf:datatype="xsd:string">compound accumulation in lysosome [Phospholipidosis (latent)]</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0004933 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0004933">
        <rdfs:label rdf:datatype="xsd:string">negative regulation of phospholipid degradation [Phospholipidosis (latent)]</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0005059 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0005059">
        <rdfs:label rdf:datatype="xsd:string">hypofunction of phospholipid degradation [Phospholipidosis(latent)]</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0005189 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0005189">
        <rdfs:label rdf:datatype="xsd:string">phospholipid biosynthetic process [Phospholipidosis(latent)]</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



