has result has context reactive oxygen species biosynthetic process mitochondrial respiratory chain abnormality [Mitochondrial disorder] mitochondrial dysfunction [Mitochondrial disorder] increasing demand for response to mitochondrial oxidative stress [Mitochondrial disorder] mitochondrial damage [toxic course] mitochondrial disorder dependent process reactive oxygen species biosynthetic process [Mitochondrial disorder] PMID:23299992 PMID:25339807 PMID:26571396 PMID:27151080 PMID:29222479 PMID:29335519 PMID:30232152 PMID:31623280 PMID:31649547 The chemical reaction resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. This entity is a specific course-dependent process. This process can constitute the course of Mitochondrial disorder. positive regulation of mitochondrial membrane permeability [Mitochondrial disorder] DNA damage [Mitochondrial disorder] negative regulation of oxidative phosphorylation [Mitochondrial disorder] JNK signaling (primitive) [mitochondrial disorder] tumor necrosis factor production [mitochondrial disorder] release of DNA from mitochondria [mitochondria disorder] metabolic dysfunction of precursor metabolites and energy generation [mitochondrial disorder] cytokine production involved in inflammatory response [mitochondrial disorder] lipoperoxidation [mitochondrial disorder] IL6 signaling [Mitochondrial disorder] cardiolipin peroxidation [mitochondrial disorder] IL-1beta production [mitochondrial disorder] Insulin resistance (process) [mitochondrial disorder] Calcium ion homeostasis imbalance [mitochondrial disorder] Hypofunction of sequestering of calcium ion in ER [mitochondrial disorder] mitochondria morphology change [mitochondrial disorder] redox changes [mitochondrial disorder]