has part has context IRE1 signaling (primitive) endoplasmic reticulum stress [toxic course] IRE1 signaling (primitive) [ER stress] IRE1 signaling (primitive) is a subtype of signaling [biological]: A process that in which a signal is transmitted by the IRE1 (Inositol-requiring transmembrane kinase/endonuclease). IRE1 generally plays a endoplasmic reticulum membrane stress sensor role. This entity is a specific course-dependent process. This process can constitute the course of ER stress. IRE1 activation [IRE1 pathway] ER stress dependent process (molecular level)