participates in has role protein refolding [ER stress (early stage)] GRP78 (canonical)[ER stress] negative regulator role of stress sensor GRP78 - stress sensor inhibitor (canonical)[ER stress - proteinrefolding [persist] -ATF6 pathway] BIP- stress sensor inhibitor[ER stress - proteinrefolding [persist] -ATF6 pathway] HEL-S-89n- stress sensor inhibitor [ER stress - proteinrefolding [persist] -ATF6 pathway] HSPA5- stress sensor inhibitor [ER stress - proteinrefolding [persist] -ATF6 pathway] Heat Shock Protein Family A (Hsp70) Member 5- stress sensor inhibitor [ER stress - proteinrefolding [persist] -ATF6 pathway] MIF2- stress sensor inhibitor[ER stress - proteinrefolding [persist] -ATF6 pathway]