has molecular reaction has result ERAD related gene expression [ER stress] XBP1 activation by IRE1 [ER stress - ERAD] The XBP1 gene is transcribed to yield mRNA, the mRNA is spliced to yield Xbp(s) mRNA, and the mRNA is translated to yield protein. XBP1 activation by IRE1 is a subtype of activation of transcription factor: A process that changes the activity of XBP1 (X-Box Binding Protein 1) to be higher by IRE1. This entity is a specific course-dependent process. This process is dependent on the ERAD process and can constitute the course of ER stress. http://www.reactome.org/PathwayBrowser/#/R-HSA-381183&SEL=R-HSA-1791121&PATH=R-HSA-392499,R-HSA-381119,R-HSA-381033 XBP1 activation by IRE1 [ER stress] XBP1 splicing [ER stress - ERAD]