has participant has molecular reaction has context XBP1 splicing [ER stress] XBP1 (canonical)[ER stress] endoplasmic reticulum stress [toxic course] XBP1 activation by IRE1 [IRE1 pathway] XBP1 activation by IRE1 [ER stress] Reactome:R-HSA-1791121.3 The XBP1 gene is transcribed to yield mRNA, the mRNA is spliced to yield Xbp(s) mRNA, and the mRNA is translated to yield protein. XBP1 activation by IRE1 is a subtype of activation of transcription factor: A process that changes the activity of XBP1 (X-Box Binding Protein 1) to be higher by IRE1. This entity is a specific course-dependent process. This process can constitute the course of ER stress. ER stress dependent process (molecular level)