has role glyburide cholestasis dependent chemical compound inhibitor role of BSEP bile acid transport glibenclamide [Cholestasis] An urea that has formula C23H28ClN3O5S. CASRN:10238-21-8 DrugBank:DB01016 InChIKeyZ:NNLBTZKUZBEKO-UHFFFAOYSA-N OATP transporters are a critical factor controlling the uptake of glibenclamide by the liver. GLB is a substrate for OATP2B1 and OATP1B1, which are expressed at the sinusoidal membrane of hepatocytes. Wikipedia:Glyburide rifampicin, cyclosporine A, rifamycin SV, bosentan, troglitazone, erythromycin estolate, and glibenclamide inhibit Bsep in rats