has part has result Bcl2 inactivation by JNK [ER stress - apoptosis - IRE1-TRAF2-JNK pathway] A process that changes the activity of the Bcl2 to be lower by JNK. This process is dependent on the IRE1-TRAF2-JNK pathway mediated apoptosis and can constitute the course of ER stress. Inhibition of anti-apoptotic factor Bcl-2 results in the promotion of apoptosis. Bcl2 inactivation by JNK BIM activation [ER stress - apoptosis - IRE1−TRAF2-JNK-Bcl2 pathway] Bcl2 phosphorylation by JNK [ER stress]