has context has agent negative regulation of formation of cytoplasmic translation initiation complex endoplasmic reticulum stress [toxic course] P-EIF2A - translation initiation inhibitor (canonical)[ER stress - translation attenuation] negative regulation of formation of cytoplasmic translation initiation complex by eIF2a [ER stress - inflammation] Negative regulation of formation of cytoplasmic translation initiation complex is a subtype of negative regulation process: A process that stops, prevents, or reduces the frequency, rate or extent of formation of cytoplasmic translation initiation complex. This process is dependent on the inflammation and can constitute the course of ER stress. PMID:23334697 PMID:9930704 ER stress dependent process (molecular level)