has molecular reaction has result has context has agent endoplasmic reticulum stress [toxic course] receiving signal by ATF6 [ATF6 pathway] ATF6 signaling (primitive) [ER stress - apoptosis] receiving abnormal protein signal by ATF6 [ER stress - apoptosis] Receiving abnormal protein signal by ATF6 is a subtype of receiving signal: A process that recognizes another object and changes into an abnormal protein (e.g., misfolded protein, etc.) signal by ATF6. This process is dependent on the apoptosis and can constitute the course of ER stress. Dissociation of ATF6-alpha:BIP Complex [ER stress - apoptosis] ATF6 - stress sensor (canonical)[ER stress - apotosis] ER stress dependent process (molecular level)