has role relateds assay FADs2 (mol) in vivo assay phospholipidosis dependent molecule (canonical) FADS2 (canonical)[Phospholipidosis] Delta-6 Fatty Acid Desaturase [Phospholipidosis] Fatty Acid Desaturase 2 Delta-6 Fatty Acid Desaturase [Phospholipidosis] Linoleic acid (LA) metabolism，Fatty acid metabolism PMID:19875987 The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] http://www.ncbi.nlm.nih.gov/gene/9415 NCBI-Rat-GeneID:83512 http://omim.org/entry/606149 linoleoyl-CoA desaturase role