has part has result smooth endoplasmic reticulum proliferation in hepatocyte (sustained) [Ground glass appearance] regulation of generation of precursor metabolites and energy (sustained) [Ground glass appearance] Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. This process persists for a certain period or over a long period. This entity is a specific course-dependent process. This process can constitute the course of Ground glass appearance (sustained) . negative regulation of ATP consuming via CAR activation (sustained) [Ground glass appearance] increasing AMP/ATP ratio (sustained) [Ground glass appearance] regulation of generation of precursor metabolites and energy by phenobarbital [Ground glass appearance]