liver cancer dependent molecule CCNB2 [Hepatocarcinogenesis] Cyclin B2 and p53 control proper timing of centrosome separation. PMID:9539739 A centrosomal route for cancer genome instability. Cyclin B2 is now shown to control a pathway - involving the centrosomal kinases aurora A and Plk1 and the tumour suppressor p53 - the alteration of which causes defective centrosome separation, aneuploidy and tumour development.  PMID:24875738 PMID:17533373 PMID:20660152 PMID:24324638 PMID:24875738 PMID:9539739 PMID:9926943 cyclin B2 NCBI-Human-GeneID:9133 NCBI-Rat-GeneID:363088 NCBI-Mouse-GeneID:12442 CCNB2 (mol)