occurs in has result has context mitochondrion malfunctioning of TCA cycle mitochondrial damage [toxic course] mitochondrial disorder dependent process negative regulation of respiratory electron transport chain [Mitochondrial disorder] negative regulation of oxidative phosphorylation [Mitochondrial disorder] malfunctioning of TCA cycle [Mitochondrial disorder] Malfunctioning of TCA cycle is a subtype of malfunctioning of metabolism: A process that cannot perform a tricarboxylic acid cycle appropriately or cannot realize it at all. This entity is a specific course-dependent process. This process can constitute the course of Mitochondrial disorder. PMID:26571396 PMID:29335519 increasing acetyl CoA [Mitochondrial disorder] Inflammatory response [mitochondrial disorder] gluconeogenesis [mitochondrial disorder] lipid biosynthetic process [mitochondrial disorder] increasing demand for response to oxidative stress [mitochondrial disorder]