positively regulates has result has context mitochondrial damage [toxic course] mitochondrial disorder dependent process negative regulation of respiratory electron transport chain [Mitochondrial disorder] negative regulation of oxidative phosphorylation [Mitochondrial disorder] oxidative phosphorylation uncoupling positive regulation of oxidative phosphorylation uncoupling positive regulation of oxidative phosphorylation uncoupling [Mitochondrial disorder] Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupling. Oxidative phosphorylation uncoupling is a process that enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. This entity is a specific course-dependent process. This process can constitute the course of Mitochondrial disorder.