has result has context release of cytochrome c from mitochondria mitochondrial respiratory chain abnormality [Mitochondrial disorder] mitochondrial damage [toxic course] mitochondrial disorder dependent process apoptotic process [Mitochondrial disorder] release of cytochrome c from mitochondria [mitochondrial disorder] PMID:23299992 PMID:25339807 PMID:28789970 The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation. This entity is a specific course-dependent process. This process can constitute the course of Mitochondrial disorder.