has result has context liver carcinogenesis dependent process negative regulation of adherens junction assembly hepatocarcinogenesis [toxic course] tumor cell invasion [hepatocarcinogenesis] metastasis [hepatocarcinogenesis] Tumor cell proliferation [Hepatocarcinogenesis] Negative regulation of adherens junction assembly [hepatocarcinogenesis] Negative regulation of adherens junction assembly is a subtype of negative regulation process: A process that stops, prevents, or reduces the frequency, rate or extent of adherens junction assembly. This entity is a specific course-dependent process. This process can constitute the course of hepatocarcinogenesis. PMID:17428255 TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.