<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/UBERON?iri=http://purl.obolibrary.org/obo/UBERON_0001305"?>
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     xml:base="http://www.w3.org/2002/07/owl"
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     xmlns:owl="http://www.w3.org/2002/07/owl#"
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     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
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     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000116"/>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000001"/>
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/depiction"/>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002175"/>
    


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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002202 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002202">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>develops from</rdfs:label>
        <rdfs:label xml:lang="en">develops from</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CL_0000023 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000023">
        <rdfs:label>oocyte</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0002174 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0002174">
        <rdfs:label>follicular cell of ovary</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000038 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000038">
        <rdfs:label>follicular fluid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001305 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001305">
        <rdfs:label>ovarian follicle</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_8450001"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0002174"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000023"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005296"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000038"/>
            </Restriction>
        </rdfs:subClassOf>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/c/ca/Human_ovarian_follicle.jpg</foaf:depiction>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://upload.wikimedia.org/wikipedia/commons/e/e6/Primary_follicle-4.JPG</foaf:depiction>
        <oboInOwl:hasRelatedSynonym>egg follicle</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>ovary follicle</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>CALOHA:TS-0726</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:371</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0001110</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006080</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>follicle of ovary</oboInOwl:hasExactSynonym>
        <oboInOwl:id>UBERON:0001305</oboInOwl:id>
        <oboInOwl:hasDbXref>BTO:0000475</oboInOwl:hasDbXref>
        <ns3:UBPROP_0000008>These structures are periodically initiated to grow and develop, culminating in ovulation of usually a single competent oocyte in humans. These eggs/ova are only developed once every menstrual cycle (e.g. once a month in humans)</ns3:UBPROP_0000008>
        <oboInOwl:hasDbXref>Wikipedia:Ovarian_follicle</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000449</oboInOwl:hasDbXref>
        <ns3:UBPROP_0000003>Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG]</ns3:UBPROP_0000003>
        <oboInOwl:hasDbXref>SCTID:361111009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0018120</oboInOwl:hasDbXref>
        <ns3:UBPROP_0000009>The somatic cell component of the follicle produces hormones important for oocyte development and proper endocrine function</ns3:UBPROP_0000009>
        <oboInOwl:hasDbXref>MA:0001707</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001536</oboInOwl:hasDbXref>
        <ns3:UBPROP_0000001>Oocyte development of zebrafish has been divided into five stages based on morphological criteria and on physiological and biochemical events. Stage I follicles (less than 140 microns) are primary growth stage, stage II follicles (140-340 microns) are cortical alveolus stage, stage III (340-690 microns) are vitellogenesis, stage IV (690-730 microns) are oocyte maturation, and stage V follicles are matured egg. Selman et al, 1993.[TAO]</ns3:UBPROP_0000001>
        <oboInOwl:hasDbXref>NCIT:C33244</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>follicle of ovary viewed macroscopically</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>EMAPA:35627</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0001110</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:18640</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified].</ns3:IAO_0000115>
        <ns3:IAO_0000116>TODO - align subtypes based on staging, which is taxon-specific</ns3:IAO_0000116>
        <oboInOwl:hasRelatedSynonym>folliculi ovarici primarii</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>folliculi ovarici vesiculosi</oboInOwl:hasRelatedSynonym>
        <ns3:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#mouse_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#vertebrate_core"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004120 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004120">
        <rdfs:label>mesoderm-derived structure</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0005296 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005296">
        <rdfs:label>ovary sex cord</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_8450001 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_8450001">
        <rdfs:label>egg follicle</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



