part of part of has part has part adjacent to adjacent to composed primarily of Langerhans cell spinous cell of epidermis Homo sapiens skin epidermis stratum basale of epidermis stratum spinosum of epidermis UBERON:0002026 epidermis stratum spinosum Wikipedia:Stratum_spinosum Malpighian layer epidermis prickle cell layer stratum Malpighii prickle cell layer stratum spinosum The layer of polyhedral cells in the epidermis found between the stratum granulosum and stratum basale; shrinkage and adhesion of these cells gives a spiny or prickly appearance. BTO:0000435 squamous cell layer of epidermis prickle cell layer of epidermis MA:0000807 UMLS:C0221924 Has cells that produce and secrete bipolar lipids which prevent evaporation, helping to 'water-proof' the skin. Keratinization begins in the stratum spinosum. [Wikipedia:Stratum_spinosum] NCIT:C12850 FMA:67542 SCTID:420086000 EMAPA:32785 stratum granulosum of epidermis integumentary system layer