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    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002176 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002176">
        <rdfs:label>connects</rdfs:label>
        <rdfs:label xml:lang="en">connects</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0002202 -->

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        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>develops from</rdfs:label>
        <rdfs:label xml:lang="en">develops from</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

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    <!-- http://purl.obolibrary.org/obo/UBERON_0002050 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002050">
        <rdfs:label>embryonic structure</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002081 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002081">
        <rdfs:label>cardiac atrium</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/UBERON_0002082 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002082">
        <rdfs:label>cardiac ventricle</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002087 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002087">
        <rdfs:label>atrioventricular canal</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002050"/>
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        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/d/d8/Gray464.png</foaf:depiction>
        <oboInOwl:hasRelatedSynonym>ependymal canal</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Atrioventricular_canal</oboInOwl:hasDbXref>
        <oboInOwl:id>UBERON:0002087</oboInOwl:id>
        <oboInOwl:hasExactSynonym>atrial canal</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ZFA:0001315</oboInOwl:hasDbXref>
        <ns5:UBPROP_0000001>The canal connecting the primitive atrium and ventricle in fishes and amniotes embryo. [TFD][VHOG]</ns5:UBPROP_0000001>
        <oboInOwl:hasRelatedSynonym>canalis atrioventricularis</oboInOwl:hasRelatedSynonym>
        <ns5:IAO_0000115>The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP].</ns5:IAO_0000115>
        <oboInOwl:hasExactSynonym>atrio-ventricular canal</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>EMAPA:16546</oboInOwl:hasDbXref>
        <ns5:UBPROP_0000011>The right side of the AVC becomes the tricuspid valve whereas the left side of the AVC will become the bicuspid valve</ns5:UBPROP_0000011>
        <ns5:UBPROP_0000009>In the embryo, the atrioventricular canal delays the impulse from atrium to ventricle[PMID:22984480]</ns5:UBPROP_0000009>
        <oboInOwl:hasDbXref>TAO:0001315</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>AVC</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>EHDAA:764</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:341079007</oboInOwl:hasDbXref>
        <ns5:UBPROP_0000003>The heart is the first organ to form and function in a vertebrate. (...) Septation of the AV canal is initiated with the formation of inferior and superior endocardial cushions in response to signaling from the overlying myocardium. (...) Analysis of zebrafish mutants with cardiovascular defects uncovered a previously unexpected level of conservation between zebrafish and human cardiovascular physiology.[uncertain][VHOG]</ns5:UBPROP_0000003>
        <oboInOwl:hasDbXref>VHOG:0001473</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:71121</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0004123</oboInOwl:hasDbXref>
        <ns5:UBPROP_0000012>this is a lumen in EHDAA2</ns5:UBPROP_0000012>
        <oboInOwl:hasExactSynonym>AV canal</oboInOwl:hasExactSynonym>
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        <dcterms:contributor rdf:resource="https://orcid.org/0000-0001-9114-8737"/>
        <dcterms:contributor rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004141 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004141">
        <rdfs:label>heart tube</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0007279 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0007279">
        <rdfs:label>presumptive atrioventricular canal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0011820 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0011820">
        <rdfs:label>atrioventricular region</rdfs:label>
    </Class>
    


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    <!-- https://orcid.org/0000-0001-9114-8737 -->

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        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <rdfs:label>Melissa Haendel</rdfs:label>
    </NamedIndividual>
    


    <!-- https://orcid.org/0000-0002-6601-2165 -->

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        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <rdfs:label>Christopher J. Mungall</rdfs:label>
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