part of part of has part has part develops from develops from has developmental contribution from has developmental contribution from parafollicular cell CALCA gene translation product endocrine system neural crest endocrine gland ultimobranchial body ultimopharyngeal body Wikipedia:Ultimopharyngeal_body ultimopharyngeal gland telobranchial body EHDAA:9139 In humans, the ultimobranchial body is an embryological structure that gives rise to the calcitonin-producing cells - also called parafollicular cells or clear cells - of the thyroid gland. In humans, this body is a derivative of the ventral recess of the fourth pharyngeal pouch (or fifth) XAO:0000452 TODO - ensure developmental relationships correct across species. WP says pouch 4, but this isn't supported by Kardong (table 13.1 or fig 15.5). MP says 'fifth pouch in human or as the ventral component of the fourth pouch in mouse'. EHDAA2 says 6th arch mesenchyme http://www.ncbi.nlm.nih.gov/pubmed/16313389 says: the most posterior pouch generates the ultimobranchial bodies in most vertebrate classes, but mammals do not contain this structure telopharyngeal body postbranchial body MESH:D014460 ultimobranchial TAO:0001448 EHDAA:2987 The ultimobranchial bodies of lower vertebrates contain large amounts of calcitonin. In mammals the bodies fuse with the thyroid gland and are thought to develop into the parafollicular cells. (Stedman, 25th ed) An outpocketing of one of the caudal pharyngeal pouches that is comprised on calcitonin-producing parafollicular cells. AAO:0010547 ZFA:0001448 EHDAA2:0002103 (...) ultimobranchial bodies that develop in all vertebrates from the ventral or posterior surface of the last pair of pharyngeal pouches. The ultimobranchial bodies are vestigial in most mammals (...).[well established][VHOG] EMAPA:36030 corpus ultimopharyngeum GAID:1246 ultimobranchial bodies SCTID:345552007 ultimobranchial gland Anatomical structure which includes small, calcitonin producing glands originating as epithelial growths from the sixth pharyngeal pouch.[AAO] VHOG:0001185 UBERON:0003092 The glandular tissue originating from the fifth branchial pouch which combines with the buccal cavity outgrowth to form the thyroid and contributes calcitonin-secreting cells to the gland. [TFD][VHOG] pharyngeal pouch endoderm-derived structure structure with developmental contribution from neural crest