part of part of bone marrow skull bone marrow of skull 2026-08-20T04:59:35Z https://github.com/obophenotype/uberon/pull/3758 skull BM SCTID:712962003 ('Structure of bone marrow of cranium') is scoped to the cranium rather than the whole skull, so it excludes mandibular marrow that this class admits; its SNOMED children cover frontal, temporal, sphenoid and nasal-orbit marrow. The FMA has no corresponding grouping class - it descends from 'Bone marrow of flat bone' (FMA:303320) straight to per-bone classes such as FMA:303380 (frontal), FMA:303382 (parietal), FMA:303388 (occipital) and FMA:303454 (temporal) - so no FMA xref is asserted here. skull bone marrow Distinguished from other bone marrow sites (for example sternal, femoral, tibial or vertebral marrow) by its direct osseous connection to the dura mater. Reported to contain lymphoid structures with germinal-centre-like features that respond to central nervous system-derived antigens (PMID:42618784). SCTID:712962003 In the neuroimmunology literature 'skull bone marrow' is generally used for calvarial marrow specifically (see 'bone marrow of calvaria'); marrow of the basicranium (UBERON:0002517) is sampled and reported as a separate compartment, as are vertebral, sternal and femoral marrow. Annotate to 'bone marrow of calvaria' where the calvaria is what was sampled. A bone marrow that is located within the bones of the skull. In mammals, skull bone marrow is haematopoietically active and communicates directly with the dura mater through osseous skull channels, which permit the exchange of cerebrospinal fluid, central nervous system-derived antigens and immune cells; it acts as a local reservoir of myeloid cells and B cells for the meninges and the central nervous system. cranial bone marrow UBERON:1200342 Christopher J. Mungall