part of part of vault of skull bone marrow of skull bone marrow of calvaria 2026-08-20T04:59:35Z https://github.com/obophenotype/uberon/pull/3758 calvarial marrow UBERON:1200343 In the mouse, lymphoid clusters containing follicular helper-like T cells, B cells and follicular dendritic cells are enriched in the marrow of the occipital and interparietal regions and are sparse in the frontal and parietal regions (PMID:42618784). Neither the FMA nor SNOMED has a calvarial marrow grouping class. The FMA covers the same territory with per-bone classes: FMA:303380 (frontal), FMA:303382 (parietal), FMA:303388 (occipital) and FMA:303390 (sutural bone); these are the natural xref targets if regional calvarial marrow terms are added. A bone marrow of skull that is located within the diploic spaces of the calvaria (skull vault). It is the principal haematopoietic compartment of the mammalian skull and is connected to the dura mater by transcalvarial channels; its immune composition differs between anterior (frontal, parietal) and posterior (interparietal, occipital) territories. The differentia uses 'vault of skull' (UBERON:0004339), whose own comment records that the vault may not be precisely equivalent to the calvaria - sources differ on whether the temporal, ethmoid and sphenoid bones are included. That ambiguity is inherited here rather than introduced: this class is intended as the marrow of whatever 'vault of skull' covers, which is the compartment the calvarial bone marrow literature samples. calvarial bone marrow skull cap bone marrow Christopher J. Mungall