part of part of has input has input has output has output process reaction (2R,3R)-2,3-dihydroxy-3-methylpentanoic acid + NADP(+) = (R)-3-hydroxy-3-methyl-2-oxopentanoate + H(+) + NADPH 1 1 1 1 1 1 reaction UPa:UCR05068 KEGG:R05068 L-isoleucine from 2-oxobutanoate: step 2/4 NADPH NADP(+) H(+) (2R,3R)-2,3-dihydroxy-3-methylpentanoic acid (R)-3-hydroxy-3-methyl-2-oxopentanoate