enterobactin biosynthesis pathway enterochelin biosynthesis Biosynthesis of siderophore enterobactin, a compound that transports iron from the bacterial environment into the cell cytoplasm. In Escherichia coli, the siderophore molecule enterobactin is synthesized in response to iron deprivation by formation of an amide bond between 2,3-dihydroxybenzoate (2,3-DHB) and l-serine and formation of ester linkages between three such N-acylated serine residues. PMID:9485415 PMID:17675380 PMID:9214294 UPa:UPA00017 GO:0009239 siderophore biosynthesis