L-lysine biosynthesis via AAA pathway PMID:15522288 PMID:3928261 PMID:16943623 PMID:16232683 L-lysine biosynthesis via L-2 aminoadipate pathway PMID:11029074 KEGG:map00310 PMID:11238076 KEGG:map01100 PMID:11489859 pathway MetaCyc:LYSINE-AMINOAD-PWY MetaCyc:PWY-3081 L-lysine biosynthesis via alpha aminoadipate pathway PMID:270744 L-lysine biosynthesis via aminoadipic pathway Biosynthesis of L-lysine through the alpha-amino adipic acid (AAA) pathway. It was first believed that this pathway was a specific character of fungi. In 1998, a gene cluster of a thermophilic bacterium (Thermus thermophilus) was shown to synthesize L-lysine through the AAA pathway. This pathway is present in hyperthermophilic archaea too (P. horikoshii and P. abyssi). Hence, this pathway is distributed among the three super-kingdoms as proposed by Woese and Fox in 1997 [PMID:270744]. KEGG:map00620 KEGG:map00300 KEGG:map01110 UPa:UPA00033 PMID:10613839 PMID:9868782 GO:0019878 amino-acid biosynthesis L-lysine biosynthesis