candicidin biosynthesis C135 biosynthesis GO:1901127 Biosynthesis of candicidin, an aromatic polyene (heptaene) antibiotic produced by Streptomyces griseus IMRU 3570. Polyene macrolides are a group of polyketides with lactone rings of 20-44 members. Candicidin was first described by Lechevalier et al. (1953) and named antibiotic C135, although it was renamed candicidin because of its strong activity against species of Candida. pathway UPa:UPA00101 PMID:11782498 candicidin D biosynthesis PMID:12664141 antibiotic biosynthesis polyketide biosynthesis