pyocyanine biosynthesis UPa:UPA00235 pathway Biosynthesis of pyocyanin, a blue pigment produced by bacteria such as Pseudomonas spp. Pyocyanin is a redox-active phenazine compound that kills mammalian and bacterial cells through the generation of reactive oxygen intermediates. Pyocyanin produced by Pseudomonas aeruginosa contributes to its ability to colonise the lungs of cystic fibrosis patients. pyocyanin biosynthesis antibiotic biosynthesis secondary metabolite biosynthesis pigment biosynthesis