polyol metabolism glycerol degradation glycerol degradation via glycerol kinase pathway KEGG:map01100 KEGG:map00561 GO:0019563 In bacteria, glycerol uptake is mediated by the glycerol diffusion facilitator, an integral membrane protein catalyzing the rapid equilibration of concentration gradients of glycerol across the cytoplasmic membrane. Intracellular glycerol is converted to glycerol-3-phosphate that is further metabolized to dihydroxyacetone phosphate (DHAP) by either of two membrane-bound enzymes, depending on the growth conditions. UPa:UPA00618 pathway MetaCyc:PWY0-381 MetaCyc:PWY-4261