catecholamine biosynthesis (R)-adrenaline biosynthesis GO:0042418 adrenaline biosynthesis Biosynthesis of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. pathway KEGG:map00350 KEGG:map01100 UPa:UPA00749