xenobiotic degradation aromatic compound degradation nitrobenzene degradation PMID:9471964 GO:1900998 UPa:UPA00923 Degradation of nitrobenzene. Pseudomonas pseudoalcaligenes JS45 utilizes nitrobenzene as the sole source of nitrogen, carbon, and energy. Some studies have shown that degradation of nitrobenzene involves the reduction of nitrobenzene to nitrosobenzene and hydroxylaminobenzene, followed by rearrangement to 2-aminophenol, which then undergoes meta ring cleavage to 2-aminomuconic semialdehyde. Comamonas sp. JS765 can also use nitrobenzene as the sole source of carbon, nitrogen, and energy. It inserts dioxygen directly into nitrobenzene, with concomitant reduction of the substrate to form catechol. pathway PMID:9573204