<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/UPHENO?iri=http://purl.obolibrary.org/obo/CHEBI_28940"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:chebi="http://purl.obolibrary.org/obo/chebi#3"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_176497 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_176497">
        <rdfs:label>geroprotector</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_26764 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_26764">
        <rdfs:label>steroid hormone</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_28940 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28940">
        <rdfs:label>calciol</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_26764"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35681"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_36818"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_73558"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_176497"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_77746"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasAlternativeId>CHEBI:10008</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>PMID:16886665</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12174089</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB00169</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10347174</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Cholecalciferol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>activated 7-dehydrocholesterol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>KEGG:C05443</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Cholecalciferol</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:46283</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>PMID:9627702</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2997282</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:VD3</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>calciol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>CAS:67-97-0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17156784</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:2840</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2838261</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:2339331</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0000876</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:6265326</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:23170</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>PMID:15214747</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>CC</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vitamin D3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>KEGG:D00188</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:3494111</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>PMID:15876428</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:184223</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24304198</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>vitamin D3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:28940</oboInOwl:id>
        <oboInOwl:hasRelatedSynonym>(1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Gmelin:1267613</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12955389</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11493580</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>A hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.</ns4:IAO_0000115>
        <oboInOwl:hasRelatedSynonym>colecalciferol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(+)-vitamin D3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>oleovitamin D3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:19817701</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23964472</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>LIPID_MAPS_instance:LMST03020000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PPDB:160</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>LIPID_MAPS_instance:LMST03020001</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35681 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35681">
        <rdfs:label>secondary alcohol</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_36818 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_36818">
        <rdfs:label>seco-cholestane</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_73558 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_73558">
        <rdfs:label>D3 vitamins</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_77746 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_77746">
        <rdfs:label>human metabolite</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



