has role polypeptide peptide hormone antineoplastic agent appetite enhancer antiatherogenic agent apoptosis inducer ghrelin pubmed:23307791 pubmed:28538835 wikipedia.en:Ghrelin pubmed:23178701 pubmed:23317782 pubmed:28542403 H-Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH pubmed:23982275 pubmed:23704134 pubmed:23159561 pubmed:23359315 pubmed:15788704 pubmed:23278489 pubmed:28621678 kegg.compound:C16025 pubmed:23316086 pubmed:23652399 Ghrelin (human) pubmed:23965296 GSS(octanoyl)FLSPEHQRVQQRKESKKPPAKLQPR pubmed:23804489 CHEBI:75431 pubmed:23698230 pubmed:23989358 GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR Human ghrelin Gastric MLTRP pubmed:23481295 pubmed:23624808 pubmed:23843943 pubmed:23652386 cas:304853-26-7 pubmed:23652420 Motilin-related peptide reaxys:24715767 pubmed:23778458 pubmed:23847595 cas:258279-04-8 pubmed:23631903 pubmed:28704966 pubmed:23808302 pubmed:23428971 pubmed:28547758 A 28-membered appetite-stimulating polypeptide consisting of Gly, Ser, Ser(octanoyl), Phe, Leu, Ser, Pro, Glu, His, Gln, Arg, Val, Gln, Gln, Arg, Lys, Glu, Ser, Lys, Lys, Pro, Pro, Ala, Lys, Leu, Gln, Pro and Arg residues joined in sequence. The <em>O</em>-<em>n</em>-octanoylation of the side-chain hydroxy group of serine-3 (Ser3) is essential for ghrelin's activity. pubmed:28590260 pubmed:23524619 chebi_ontology Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg human metabolite