has participant water hydron NAD(1-) NADH(2-) L-allysine zwitterion L-2-aminoadipate(1-) L-aminoadipate-semialdehyde dehydrogenase activity L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity alpha-aminoadipate reductase activity EC:1.2.1.31 alpha-aminoadipate-semialdehyde dehydrogenase activity aminoadipate semialdehyde dehydrogenase activity 2-aminoadipic semialdehyde dehydrogenase activity L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase Reactome:R-HSA-70941 GO:0004043 AAR RHEA:12308 aminoadipate-semialdehyde dehydrogenase activity molecular_function MetaCyc:1.2.1.31-RXN 2-aminoadipate semialdehyde dehydrogenase activity Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+. oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor