has participant pyruvate hydron oxaloacetate(2-) hydrogencarbonate ATP(4-) hydrogenphosphate ADP(3-) pyruvate carboxylase activity molecular_function Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H+ + oxaloacetate + phosphate. MetaCyc:PYRUVATE-CARBOXYLASE-RXN pyruvate:carbon-dioxide ligase (ADP-forming) GO:0004736 Reactome:R-HSA-70501 RHEA:20844 pyruvic carboxylase activity KEGG_REACTION:R00344 EC:6.4.1.1 ligase activity, forming carbon-carbon bonds