phenotype affects entity ketone body biosynthetic process Abnormality of metabolism/homeostasis Ketosis UMLS:C0022638 HP:0001946 Presence of elevated levels of ketone bodies in the body. SNOMEDCT_US:213281004 Hyperketosis SNOMEDCT_US:2538008 UMLS:C0235430 Ketone bodies are formed from acetyl-CoA in the liver by ketogenesis when the liver glycogen stores are depleted. Ketone bodies are acidic, and ketoacidosis ensues if the compensatory mechanisms are overloaded. The predominant ketones being acetoacetate, acetone, and beta-hydroxybutyrate. HP:0003543 ketosis increased ketone body biosynthetic process