<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/UPHENO?iri=http://purl.obolibrary.org/obo/HP_0002846"?>
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     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
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    //
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="https://w3id.org/semapv/vocab/crossSpeciesExactMatch"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/UPHENO_0000001 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/UPHENO_0000001">
        <rdfs:label>phenotype affects entity</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CL_0000236 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000236">
        <rdfs:label>B cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0002846 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0002846">
        <rdfs:label>Abnormal B cell morphology</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004332"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UPHENO_7000394"/>
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            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/UPHENO_0000001"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000236"/>
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        <rdfs:comment>B cells are bursal or bone marrow-derived lymphocytes whose principle function in the adaptive immune system is to make antibodies against antigens. A simple definition of B lymphocytes is a population of cells that express clonally diverse cell surface immunoglobulin (Ig) receptors recognizing specific antigenic epitopes. Over 10 B cell-specific cell surface molecules have been identified by monoclonal antibodies, including CD19, which is considered a pan-B cell and possibly follicular dendritic cell marker, and CD20, which is considered to be a marker for mature B cells.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Abnormal B cells</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0002846</oboInOwl:id>
        <ns4:IAO_0000115>A structural abnormality of B cells.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Abnormality of B cells</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C4021748</oboInOwl:hasDbXref>
        <ns5:crossSpeciesExactMatch rdf:resource="http://purl.obolibrary.org/obo/MP_0004939"/>
        <ns5:crossSpeciesExactMatch rdf:resource="http://purl.obolibrary.org/obo/UPHENO_7000394"/>
        <ns5:crossSpeciesExactMatch rdf:resource="http://purl.obolibrary.org/obo/XPO_0103150"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0004332 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0004332">
        <rdfs:label>Abnormal lymphocyte morphology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0004939 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0004939">
        <rdfs:label>abnormal B cell morphology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UPHENO_7000394 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UPHENO_7000394">
        <rdfs:label>b cell morphology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/XPO_0103150 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/XPO_0103150">
        <rdfs:label>abnormal B-cell morphology</rdfs:label>
    </Class>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



