phenotype affects entity myeloid dendritic cell abnormal dendritic cell physiology abnormal Langerhans cell physiology MP:0005362 atypical or failure of normal function of the stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus MPheno.ontology abnormal Langerhans cell function myeloid dendritic cell physiology phenotype