Semilobar holoprosencephaly holoprosencephaly semilobar holoprosencephaly 2023-07-25T16:04:50Z semilobar HPE MP:0014278 a type of holoprosencephaly with partial division of the brain into two hemispheres, fusion of the hemispheres is present in the frontal and parietal lobes with the interhemispheric fissure present only in the back of the brain semilobar holoprosencephaly