Macrovesicular hepatic steatosis hepatic steatosis macrovesicular hepatic steatosis 2020-07-07T12:25:03Z large droplet steatosis a common form of hepatic steatosis characterized by the presence of large lipid droplets that displace the nucleus and organelles to the cell periphery in affected hepatocytes; may be caused by oversupply of lipids due to obesity, obstructive sleep apnea, insulin resistance, or alcoholism macrovesicular steatosis MP:0031115 MPheno.ontology macrovesicular hepatic steatosis