<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/UPHENO?iri=http://purl.obolibrary.org/obo/MP_0031224"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
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     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
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    <!-- 
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date"/>
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/UPHENO_0000001 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/UPHENO_0000001">
        <rdfs:label>phenotype affects entity</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
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    <!-- http://purl.obolibrary.org/obo/MP_0008721 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0008721">
        <rdfs:label>abnormal chemokine level</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MP_0031224 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MP_0031224">
        <rdfs:label>abnormal CXCL10 level</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MP_0008721"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/UPHENO_0000001"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000006064"/>
            </Restriction>
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        <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-12-22T12:32:14Z</dc:date>
        <oboInOwl:hasOBONamespace>MPheno.ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym>abnormal gamma-IP10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MP:0031224</oboInOwl:id>
        <oboInOwl:hasExactSynonym>abnormal interferon gamma-induced protein 10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>abnormal C-X-C motif chemokine ligand 10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>abnormal IP-10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>abnormal IP10 level</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>abnormal small-inducible cytokine B10 level</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>deviation from the normal levels of CXCL10 protein, a pro-inflammatory cytokine that is secreted by a wide range of cell types in response to interferon-gamma, and produces its effects by binding to the cell surface chemokine receptor CXCR3; it is involved in a variety of processes including chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects, and plays an important role during viral infections by stimulating the activation and migration of immune cells to infected sites</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>abnormal IFN gamma-inducible protein 10 level</oboInOwl:hasExactSynonym>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000006064 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000006064">
        <rdfs:label>C-X-C motif chemokine 10</rdfs:label>
    </Class>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



