part of
part_of
part of
develops_from
develops from
develops from
neuron associated cell (sensu Vertebrata)
glioblast (sensu Vertebrata)
oligodendrocyte precursor cell
A progenitor cell of the central nervous system that can differentiate into oligodendrocytes or type-2 astrocytes. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons.
O-2A/OPC
CL:0002453
oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell
This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991).
O2A/OPC
http://orcid.org/0000-0002-1773-2692
The cell type from which oligodendrocytes develop. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons.
2010-11-10T02:51:34Z
tmeehan
oligodendrocyte/type-2 astrocyte progenitor cell
cell
central nervous system