part of
part_of
part of
transmembrane receptor protein tyrosine kinase signaling pathway
cellular response to vascular endothelial growth factor stimulus
vascular endothelial growth factor signaling pathway
A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
biological_process
bf
VEGF signaling
GO:0038084
In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.
2012-02-01T02:27:32Z
vascular endothelial growth factor signalling pathway
VEGF-activated signaling pathway