phenotype affects entity CD8-alpha alpha positive, gamma-delta intraepithelial T cell abnormal gamma-delta intraepithelial T cell morphology abnormal CD8-positive, gamma-delta intraepithelial T cell morphology abnormal CD8-positive, gamma-delta intraepithelial T-cell morphology abnormal intraepithelial lymphocyte morphology any structural anomaly of a CD8-positive, gamma-delta T cell of the columnar epithelia such as in the gastrointestinal tract; intraepithelial T cells often have distinct developmental pathways and activation requirements MPheno.ontology abnormal CD8-positive, gamma-delta intraepithelial T-lymphocyte morphology abnormal IEL morphology MP:0008361 abnormal CD8-positive, gamma-delta intraepithelial T lymphocyte morphology