quality of a single physical entity asplenia 01/17/2016 Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks. Vaccinations It is suggested that splenectomized persons receive the following vaccinations, and ideally prior to planned splenectomy surgery: Pneumococcal polysaccharide vaccine (not before 2 years of age). Children may first need one or more boosters of pneumococcal conjugate vaccine if they did not complete the full childhood series. Haemophilus influenzae type b vaccine, especially if not received in childhood. For adults who have not been previously vaccinated, two doses given two months apart was advised in the new 2006 UK vaccination guidelines (in the UK may be given as a combined Hib/MenC vaccine). Meningococcal conjugate vaccine, especially if not received in adolescence. Previously vaccinated adults require a single booster and non-immunised adults advised, in UK since 2006, to have two doses given two months apart. Children too young for the conjugate vaccine should receive meningococcal polysaccharide vaccine in the interim. Influenza vaccine, every winter, to help prevent getting secondary bacterial infection. (https://en.wikipedia.org/wiki/Asplenia) Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks.Asplenia is a form of immunodeficiency, increasing the risk of sepsis from polysaccharide encapsulated bacteria,and can result in overwhelming post splenectomy infection (OPSI), often fatal within a few hours. In particular, patients are at risk from Streptococcus pneumoniae, Haemophilus influenzae, and meningococcus.The risk is elevated as much as 350–fold. (https://en.wikipedia.org/wiki/Asplenia) YL YL