has role virmugen virmugen role Actinobacillus pleuropneumoniae gene apxIIID from Actinobacillus pleuropneumoniae Rebecca Racz NCBI_Nucleotide_ID: 470687; PMID: 19887737 Oliver He An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain gene