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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

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        <rdfs:label xml:lang="en">has role</rdfs:label>
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        <rdfs:label>test in lab animal model</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/DOID_11077 -->

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        <rdfs:label xml:lang="en">brucellosis</rdfs:label>
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        <rdfs:label>Mus musculus</rdfs:label>
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        <rdfs:label>Brucella abortus</rdfs:label>
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        <rdfs:label>vaccine in research role</rdfs:label>
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        <rdfs:label>live attenuated Brucella abortus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002812 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0002812">
        <rdfs:label>Brucella abortus exsA mutant vaccine</rdfs:label>
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        <ns3:IAO_0000117>Rebecca Racz</ns3:IAO_0000117>
        <ns3:VO_0001818>3260</ns3:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Brucella DeltaexsA mutant showed decreased survival in mice compared to the survival of parental strain S2308. This demonstrated that ExsA is critical for full bacterial virulence. The B. abortus exsA deletion mutant was used as a live vaccine candidate. Challenge experiments revealed that the exsA mutant strain induced superior protective immunity in BALB/c mice compared to the protective immunity induced by strain S19 or RB51</rdfs:comment>
        <ns3:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3260</ns3:IAO_0000119>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
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