<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/VO?iri=http://purl.obolibrary.org/obo/VO_0002872"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001818"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003355 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003355">
        <rdfs:label>immunizes against pathogen</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003390 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003390">
        <rdfs:label>test in lab animal model</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10090 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10090">
        <rdfs:label>Mus musculus</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_90371 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_90371">
        <rdfs:label>Salmonella enterica subsp. enterica serovar Typhimurium</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000208 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0000208">
        <rdfs:label>vaccine in research role</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002507 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0002507">
        <rdfs:label>Salmonella typhimurium vaccine</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002872 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/VO_0002872">
        <rdfs:label>Salmonella Typhimurium clpP mutant vaccine</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns3:VO_0001818>3161</ns3:VO_0001818>
        <ns3:IAO_0000117>Rebecca Racz</ns3:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <ns3:IAO_0000117>Oliver He</ns3:IAO_0000117>
        <ns3:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3161</ns3:IAO_0000119>
        <rdfs:comment>A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium</rdfs:comment>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



